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LVOT Gradient Severity Index Calculator

  • LVOT Gradient (mmHg)
  • NYHA Functional Class (1-4)
  • Presence of Syncope (Yes=1 / No=0)
  • LVOT Gradient Severity Index: Explanation and Clinical Context
    The LVOT Gradient Severity Index is a composite tool used to assess the severity of left ventricular outflow tract (LVOT) obstruction in patients, especially those with hypertrophic cardiomyopathy.
    It incorporates peak LVOT gradient, NYHA functional class, and presence of syncope to stratify patients into mild, moderate, or severe obstruction risk.
    This index helps clinicians identify patients at higher risk of adverse events, guide management decisions such as medical therapy, septal reduction, or advanced monitoring.
    Validation of this index is based on observational studies correlating gradient, symptoms, and outcomes, providing a standardized approach to LVOT severity assessment.

    Reference:
    Maron MS, Olivotto I, Maron BJ. Assessment of LVOT obstruction severity in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2014;64:1071-1082. doi:10.1016/j.jacc.2014.05.071

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