QRS Width > 150 ms Response Ratio Calculator
- QRS Width >150 ms Response Ratio: Explanation and Clinical Context
The QRS Width >150 ms Response Ratio is derived from the MADIT-CRT trial, which studied the effect of cardiac resynchronization therapy (CRT) in patients with mild heart failure and wide QRS complexes.
Patients with a QRS duration greater than 150 ms had a significantly higher likelihood of favorable response to CRT compared to those with narrower QRS complexes.
The response ratio (~1.64) indicates the relative probability of improvement in left ventricular function and reduction in heart failure events in patients with QRS >150 ms.
This tool helps clinicians estimate the likelihood of CRT efficacy based on baseline QRS duration.
Reference:
Moss AJ, et al. MADIT-CRT Trial. N Engl J Med. 2009;361:1329-1338. doi:10.1056/NEJMoa0906431
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