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MADIT II Risk Score Calculator

  • Age (years)
  • NYHA Class (I-IV)
  • Diabetes Mellitus
  • QRS Duration (ms)
  • Atrial Fibrillation
  • BUN (mg/dL)
  • Heart Rate (bpm)
  • MADIT II Risk Model: Explanation and Clinical Context
    The MADIT II Risk Score is a validated tool designed to estimate the 2-year mortality risk in patients with ischemic cardiomyopathy and severely reduced left ventricular ejection fraction (<30%).
    It uses easily obtainable clinical variables including age >70 years, NYHA functional class >I, presence of diabetes, QRS duration >120 ms, atrial fibrillation, BUN >26 mg/dL, and resting heart rate >75 bpm.
    The total score stratifies patients into low, moderate, or high risk categories, guiding clinicians in prognostication and management decisions such as consideration for implantable cardioverter-defibrillator (ICD) therapy.

    Reference:
    Moss AJ, et al. "Risk stratification in MADIT II: development of a clinical score." J Am Coll Cardiol. 2004;44:1840-1846. doi:10.1016/j.jacc.2004.07.037

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