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NAFLD Fibrosis Score (NFS) Calculator

  • Age (years)
  • BMI (kg/m²)
  • Impaired Fasting Glucose / Diabetes (Yes=1, No=0)
  • AST (U/L)
  • ALT (U/L)
  • Platelet count (×10⁹/L)
  • Albumin (g/dL)
  • NAFLD Fibrosis Score (NFS): Explanation and Clinical Context
    The NAFLD Fibrosis Score is a non-invasive scoring system designed to estimate the likelihood of advanced fibrosis in patients with non-alcoholic fatty liver disease (NAFLD).
    It incorporates readily available clinical parameters including age, BMI, impaired fasting glucose/diabetes, AST/ALT ratio, platelet count, and albumin level.
    The resulting score stratifies patients into low, indeterminate, or high risk for advanced fibrosis, which aids clinicians in decision-making regarding further liver evaluation, such as imaging or biopsy.

    Reference:
    Angulo P, Hui JM, Marchesini G, et al. The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology. 2007;45(4):846-854. doi:10.1002/hep.21496

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