MAGGIC Heart Failure Risk Calculator
- MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) score: explanation and clinical context
The MAGGIC score is an integer-based risk score derived from an individual patient data meta-analysis of >39,000 heart-failure patients and uses 13 routinely available clinical variables to estimate medium-term mortality. The model assigns integer points to age (with points varying by EF band), LVEF categories, systolic blood pressure (SBP) by EF band, body mass index (BMI) bands, serum creatinine bands, NYHA functional class, and several binary variables including sex, current smoking, diabetes, COPD, duration of heart failure ≥18 months, and whether the patient is prescribed beta-blocker and ACE inhibitor/ARB. The integer points are summed to an overall MAGGIC score — higher scores reflect higher mortality risk. The integer score is widely used because it is simple to compute at bedside and has been externally validated in multiple cohorts for prediction of 1- and 3-year all-cause mortality; calibration may vary by population and the addition of natriuretic peptides (BNP/NT-proBNP) improves discrimination in several studies.
Reference:
Pocock SJ, Ariti CA, McMurray JJ, et al. Predicting survival in heart failure: a risk score based on 39,372 patients from 30 studies. Eur Heart J. 2013;34(19):1404–1413.
Rich JD, et al. External validation and utility in HFpEF — Circ Cardiovasc Imaging / J Am Heart Assoc validation studies provide additional confirmation of MAGGIC's utility and note improved performance when BNP is added.
Discussion
No discussions yet. Be the first to comment.