General Cardiovascular Risk Assessment Scores

ASSIGN Cardiovascular Risk Score Calculator

Clinical calculation support · Verify results before clinical use

10-Year Cardiovascular Risk Assessment

Enter the patient's risk factors to estimate 10-year ASCVD risk using the recalibrated ASSIGN v2.0 equation.

— 10-year risk

Patient characteristics

Biological sex

Age (years) ASSIGN v2.0 derivation population: 40–69 years.

Clinical risk factors

Total cholesterol (mmol/L) Use mmol/L. Convert mg/dL by dividing by 38.67.

HDL cholesterol (mmol/L) Use mmol/L. Convert mg/dL by dividing by 38.67.

Systolic blood pressure (mmHg)

Diabetes mellitus

Family history of cardiovascular disease ASSIGN v2.0 defines family history as CVD in a mother, father, or sibling; no age limit is specified.

Cigarettes smoked per day Enter 0 for a non-smoker. The equation uses cigarettes/day, not smoking status alone.

Scottish deprivation measure

Scottish Index of Multiple Deprivation (SIMD) score Enter the postcode-derived SIMD score from the official Scottish ASSIGN/SIMD lookup. Do not enter a postcode, rank, decile, or quintile. This input is Scotland-specific.

— Percent

Estimated 10-year ASCVD risk

Awaiting calculation

Complete all required fields and select Calculate Risk.

Risk threshold The Scottish ASSIGN v2.0 high-risk threshold is 10%. This threshold is specific to the Scottish prevention pathway.

This estimate is intended for primary prevention in the population for which ASSIGN v2.0 was developed. It is not validated for direct application to other countries or ethnic populations.

About the ASSIGN Score

ASSIGN (ASsessing cardiovascular risk using SIGN guidelines to assign preventive treatment) estimates the 10-year risk of a first atherosclerotic cardiovascular disease (ASCVD) event. The recalibrated ASSIGN v2.0 was developed for people living in Scotland without established cardiovascular disease.

The model includes conventional cardiovascular risk factors together with family history and socioeconomic deprivation measured using the Scottish Index of Multiple Deprivation (SIMD).

Variables included in ASSIGN v2.0

Variable	Model input
Biological sex	Male or female; sex-specific equation
Age	Years (continuous)
Total cholesterol	mmol/L (continuous)
HDL cholesterol	mmol/L (continuous)
Systolic blood pressure	mmHg (continuous)
Diabetes mellitus	Yes / no
Family history of CVD	Mother, father, or sibling
Cigarette consumption	Number per day
Socioeconomic deprivation	SIMD score / 10

Interpretation

The calculated value is the estimated percentage probability of a first ASCVD event within 10 years. Under the Scottish ASSIGN v2.0 pathway, a risk of 10% or greater is considered high risk for prevention assessment. This is not a universal treatment threshold and should not be transferred to other national guidelines without validation.

Below 10%: Below the Scottish v2.0 high-risk threshold.
10% or greater: Meets the Scottish v2.0 high-risk threshold.

People with established CVD, familial hypercholesterolaemia, or specified high-risk diabetes/CKD categories may not require risk scoring; follow the applicable guideline pathway instead.

References

Welsh P, Kimenai DM, Woodward M. Updating the Scottish national cardiovascular risk score: ASSIGN version 2.0. Heart. 2025;111(12):557–564. DOI: 10.1136/heartjnl-2024-324852.

Woodward M, Brindle P, Tunstall-Pedoe H; SIGN group on risk estimation. Adding social deprivation and family history to cardiovascular risk assessment: the ASSIGN score from the Scottish Heart Health Extended Cohort (SHHEC). Heart. 2007;93(2):172–176. DOI: 10.1136/hrt.2006.108167.

NHS Scotland / Right Decisions. ASSIGN v2.0: What is ASSIGN? Official description, variable definitions, equations, and risk threshold. Official resource.

Scottish Government. Quality Prescribing Guidance 2026–2029: Use of ASSIGN (v2.0) in cardiovascular risk stratification. Official guidance section.

Clinical disclaimer: This calculator is an educational implementation of the published ASSIGN v2.0 recalibration equation. ASSIGN v2.0 was developed and evaluated using Scottish population data and includes the Scotland-specific SIMD measure. It should not be assumed to provide calibrated risk estimates for people outside Scotland. It is designed for primary prevention and must not replace clinical assessment, current local guidelines, or clinical judgement.