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Mitral Regurgitation Severity Index (MRSI) Calculator

  • Vena Contracta Width (mm)
  • Effective Regurgitant Orifice Area (EROA, cm²)
  • Regurgitant Volume (mL/beat)
  • Left Ventricular End-Systolic Diameter (LVESD, mm)
  • Left Ventricular Ejection Fraction (LVEF, %)
  • NYHA Class
  • Mitral Regurgitation Severity Index (MRSI): Explanation and Clinical Context
    The Mitral Regurgitation Severity Index (MRSI) is a composite scoring system used to quantify the severity of mitral regurgitation (MR). It integrates echocardiographic parameters including vena contracta width, effective regurgitant orifice area (EROA), regurgitant volume, left ventricular end-systolic diameter (LVESD), left ventricular ejection fraction (LVEF), and clinical parameters such as NYHA functional class.
    Each parameter is assigned points based on clinically validated thresholds, and the total score stratifies MR into mild, moderate, severe, or very severe categories. This tool assists clinicians in assessing the hemodynamic impact of MR, guiding timing for interventions such as mitral valve repair or replacement, and predicting patient prognosis.

    Reference:
    Zoghbi WA, et al. Recommendations for Evaluation of the Severity of Native Valvular Regurgitation. J Am Soc Echocardiogr. 2017;30:303-371. doi:10.1016/j.echo.2017.01.007