T1/T2 Mapping Index: Explanation and Clinical Context The T1/T2 Mapping Index is derived from cardiac MRI T1 and T2 relaxation times, providing a quantitative assessment of myocardial tissue characteristics.
T1 mapping reflects interstitial fibrosis, edema, or infiltration, while T2 mapping is sensitive to myocardial edema.
The index (T1/T2 ratio) allows clinicians to detect early myocardial abnormalities and differentiate between acute and chronic myocardial injury.
This parameter helps guide diagnosis, prognosis, and monitoring of cardiomyopathies, myocarditis, and other myocardial pathologies.
Reference:
Messroghli DR, et al. "Modified Look-Locker Inversion recovery (MOLLI) for high-resolution T1 mapping of the heart." Magn Reson Med. 2004;52:141–146.
Giri S, et al. "T2 quantification for improved detection of myocardial edema." J Cardiovasc Magn Reson. 2009;11:56.