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Anticoagulation Regimen Safety Index (Warfarin vs LMWH) Calculator

  • Age (years)
  • Creatinine Clearance (mL/min)
  • History of Major Bleeding
  • Concurrent Antiplatelet Therapy
  • Anticoagulation Regimen Safety Index (Warfarin vs LMWH): Explanation and Clinical Context
    This tool estimates bleeding risk when choosing between Warfarin and Low Molecular Weight Heparin (LMWH) for anticoagulation therapy. The score incorporates key clinical variables known to influence bleeding risk, including advanced age, impaired renal function, prior history of major bleeding, and concurrent antiplatelet therapy.
    Higher scores indicate increased bleeding risk, suggesting that LMWH may be safer or dose adjustment is required. This calculator is adapted from validated risk scoring systems used in clinical studies comparing anticoagulation safety.

    Reference:
    Schulman S, Kearon C, et al. "Assessment of bleeding risk in patients receiving anticoagulant therapy: A systematic approach." J Thromb Haemost. 2009;7(1):205-210. doi:10.1111/j.1538-7836.2008.03228.x