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Aortic Regurgitation
Mild Moderate Severe Structural parameters Aortic leaflets Normal or abnormal Normal or abnormal Abnormal/flail, or wide coaptation defect Left ventricle (Size) Normal1 (LVEDV =150ml male, =106ml female)
Normal or mild dilated Usually dilated2 (LVEDV >150ml male, >106ml female)
Qualitative doppler RegJetwidht Regurgitation jet witdh
Small in central jets (Width in LVOT <25%)
Intermediate Large in central jets; variable in eccentric jets (Width in LVOT >65%)
Flow convergence (PISAr) None or very small (<0,3cm)
Intermediate Large (=1cm)
RegJetdensity Regurgitant jet density
(CW doppler)Incomplete or faint Dense Dense PHTRegJet3 Pressure half time of regurgitant jet
Incomplete or faint Slow (>500ms)
Medium (200-500ms)
Steep <200ms
Diastolic reversal flow in descending aorta (PW doppler)
Brief, early diastolic reversal Intermediate Prominent holodiastolic reversal Semiquantitative parameters4 VCW (cm) Vena contracta width
<0,3 0,3 - 0,6 >0,6 RegJetwidth in LVOT (%) Regurgitation jet width in LVOT (centrel jets)
<25 25-45 46-64 >65 CSARegJet in CSA LVOT (%) Regurgitation jet CSA in LVOT CSA (centrel jets)
<5 5-20 21-59 >60 Quantitative parameters4 Grade I Grade II Grade III Grade IV EROA (cm2) Effective regurgitant orifice area
<0,1 0,1 - 0,19 0,2 - 0,29 >0,3 RegVol (ml) Regurgitant volume of aortic regurgitation
<30 30 - 44 45 - 59 >60 RF (%) Regurgitant fraction of aortic valve
<30 30 - 39 40 - 49 >50 Bolded qualitative and semiquantitative signs are considered specific for their AR grade. Color Doppler usually performed at a Nyquist limit of 50-70 cm/sec.
(1) Unless there are other reasons for LV dilation. (2) Specific in normal LV function, in absence of causes of volume overload. Exception: acute AR, in which chambers have not had time to dilate. (3) PHT is shortened with increasing LV diastolic pressure and may be lengthened in chronic adaptation to severe AR. (4) Quantitative parameters can subclassify the moderate regurgitation group.
ASE Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation (2017)