Metabolic And Cardiovascular Obesity Scores

Atherogenic Index of Plasma (AIP) Calculator

Clinical calculation support · Verify results before clinical use

Lipid measurements

Use values from the same lipid profile and confirm the units before calculating.

About the Atherogenic Index of Plasma

AIP is a logarithmic index derived from the molar ratio of plasma triglycerides to HDL cholesterol. Research has associated it with lipoprotein particle size and a more atherogenic lipid profile, but it is an adjunctive marker rather than a stand-alone diagnostic test.

Formula

AIP	log₁₀ [TG (mmol/L) ÷ HDL-C (mmol/L)]
TG conversion	TG (mg/dL) ÷ 88.57 = mmol/L
HDL-C conversion	HDL-C (mg/dL) ÷ 38.67 = mmol/L

Proposed interpretive bands

AIP value	Band used by this tool
< 0.11	Lower
0.11–0.21	Intermediate
> 0.21	Higher

These categories are commonly repeated in some studies, but published cut points vary across populations and contexts. AIP should be interpreted alongside established risk assessment, the full lipid profile, comorbidities, and applicable clinical guidelines.

References

Dobiášová M, Frohlich J. The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate in apoB-lipoprotein-depleted plasma (FER(HDL)). Clin Biochem. 2001;34(7):583–588. doi:10.1016/S0009-9120(01)00212-0

Dobiášová M. Atherogenic index of plasma [log(triglycerides/HDL-cholesterol)]: theoretical and practical implications. Clin Chem. 2004;50(7):1113–1115. doi:10.1373/clinchem.2004.033175

Dobiášová M, Frohlich J, Sedová M, et al. Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography. J Lipid Res. 2011;52(3):566–571. doi:10.1194/jlr.P011668

Atherogenic index of plasma and coronary artery disease: a systematic review. 2022. Open-access systematic review. This review describes associations across studies and notes variation in AIP values and study populations.

Clinical disclaimer: This calculator is an educational aid and does not replace clinical judgement, validated cardiovascular risk assessment, or current dyslipidaemia guidelines. The displayed AIP bands should not independently determine diagnosis, treatment, or follow-up. Confirm lipid units and interpret results in the context of the individual patient.