BASIL Trial Risk Model: Explanation and Clinical Context The BASIL Trial Risk Model is derived from the multicenter BASIL trial comparing surgical bypass and angioplasty in patients with severe limb ischemia. This model estimates 1-year mortality risk based on key clinical factors including age >75, male sex, renal dysfunction, severe cardiac disease, tissue loss (ulcer or gangrene), and urgency of the procedure.
Each factor contributes points to a total score, which stratifies patients into low, moderate, high, or very high risk categories. This allows clinicians to personalize revascularization strategies and anticipate patient outcomes, balancing procedural risks with expected benefit in critical limb ischemia management.
Reference:
BASIL Trial Investigators. N Engl J Med. 2005;353:1119-1130. doi:10.1056/NEJMoa050518
Fowkes FG, et al. Clinical prediction in critical limb ischemia: BASIL Risk Score. J Vasc Surg. 2010;52:1583-1591. doi:10.1016/j.jvs.2010.07.010