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Cardiac MRI ECV Persistence Score (Post-Viral Fibrosis Risk) Calculator

  • Purpose
    Estimate the probability of persistence of interstitial myocardial fibrosis after viral myocarditis using cardiac MRI parameters. This is an experimental, literature-informed score designed for educational/decision-support use only. It is not a substitute for clinical judgment or formal guidelines.
  • Baseline global ECV (%)
  • Follow-up global ECV (%) (same scanner/protocol if possible)
  • Months between scans (baseline → follow-up)
  • Late gadolinium enhancement (LGE) present?
  • LGE extent (% of LV mass) (enter 0 if none/unknown)
  • Native T1 status at follow-up
  • Cardiac MRI ECV Persistence Score: Explanation and Clinical Context

    This tool provides an experimental composite score combining global ECV at baseline/follow-up, LGE presence and extent, and native T1 status to approximate the likelihood that interstitial myocardial fibrosis persists after viral myocarditis.

    Rationale
    ECV by cardiac MRI quantifies interstitial expansion and correlates with diffuse fibrosis. Persistent elevation after myocarditis recovery is a marker of ongoing fibrosis or remodeling. LGE identifies focal fibrosis, while T1 reflects diffuse interstitial changes.

    Clinical Interpretation
    Higher scores indicate greater likelihood of persistent fibrosis, potentially requiring closer follow-up or advanced therapy evaluation.

    Reference:
    Garg P, et al. Anatol J Cardiol. 2018.
    Yang EY, et al. Sci Rep. 2019.
    Messroghli DR, et al. CMR mapping recommendations.
    Eichhorn C, et al. JCMG. 2022.
    Joudar I, et al. Myocarditis imaging update. 2023.
    Gottbrecht M, et al. CMR normal values and variability. 2019.