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Cardiac Screening Cost-Effectiveness Model (Population-Level)

  • Population size (N)
  • Prevalence of high-risk individuals (%)
  • Screening test sensitivity (%)
  • Screening test specificity (%)
  • Screening test cost per person
  • Confirmatory test cost per positive screen
  • Annual treatment cost per true positive
  • Treatment duration / time horizon (years)
  • Annual baseline event risk in high-risk group (% per year)
  • Relative risk reduction with treatment (%)
  • Acute care cost per cardiovascular event
  • QALY loss per event
  • Discount rate (% per year)
  • Willingness-to-pay threshold per QALY
  • Cardiac Screening Cost-Effectiveness Model (Population-Level): Explanation and Clinical Context
    This calculator implements a population-level cost-effectiveness framework to evaluate cardiac screening programs that identify high-risk individuals and initiate preventive therapy. Users input epidemiologic parameters, screening performance, and cost/QALY data to estimate ICER, QALY gains, and total costs. The model applies reference-case conventions and allows rapid scenario testing for cardiac risk screening strategies.

    Reference:
    Sanders GD, et al. Recommendations of the Second Panel on Cost-Effectiveness in Health and Medicine. JAMA. 2016;316(10):1093–1103.
    Drummond MF, et al. Methods for the Economic Evaluation of Health Care Programmes. 4th ed. Oxford University Press; 2015.
    Wilson JMG, Jungner G. Principles and Practice of Screening for Disease. WHO; 1968.