CT Fractional Flow Reserve (CT FFR) Calculator
- CT Fractional Flow Reserve (FFRct): Explanation and Clinical Context
CT FFR is a non-invasive imaging-derived estimate of the pressure drop across a coronary stenosis, simulating the fractional flow reserve obtained by invasive measurement.
It integrates coronary CT angiography data with computational fluid dynamics (CFD) or simplified algorithms to predict lesion-specific ischemia.
FFRct values <0.75 generally indicate hemodynamically significant stenosis, while values >0.80 suggest non-significant lesions.
Borderline values (0.75–0.80) require careful clinical correlation with symptoms and other imaging findings.
FFRct provides clinicians a tool to stratify risk, guide revascularization decisions, and reduce unnecessary invasive angiography.
Reference:
Nørgaard BL, Leipsic J, Gaur S, et al. Diagnostic performance of non-invasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: the NXT trial. JACC Cardiovasc Imaging. 2014;7(12):1239-1252. doi:10.1016/j.jcmg.2014.07.017
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