hs-CRP Tertile Risk Category Calculator

Clinical calculation support · Verify results before clinical use

Enter laboratory value

Classify the measured hs-CRP concentration using commonly used relative cardiovascular-risk categories.

mg/L

Enter a non-negative value. Use a decimal point if needed.

About hs-CRP risk categories

High-sensitivity C-reactive protein is a marker of systemic inflammation that can provide additional information for cardiovascular risk assessment. Commonly used categories describe lower, average, and higher relative risk; they do not replace a validated global risk assessment.

hs-CRP concentrationRelative-risk category
<1.0 mg/LLower
1.0–3.0 mg/LAverage
>3.0 mg/LHigher

Important interpretation points

  • These cutoffs are commonly used relative-risk categories, not study-specific tertiles for every population.
  • hs-CRP is nonspecific and may rise with infection, inflammatory disease, trauma, or other acute conditions.
  • If the result is unexpectedly elevated during an acute illness, consider repeating measurement when clinically stable, according to clinical judgement and applicable guidance.
  • Use this result as one component of risk assessment, not as a substitute for clinical judgement.

References

Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836–843. doi:10.1056/NEJM200003233421202
Ridker PM. A Test in Context: High-Sensitivity C-Reactive Protein. J Am Coll Cardiol. 2016;67(6):712–723. doi:10.1016/j.jacc.2015.11.037
Clinical disclaimer: This calculator provides a descriptive hs-CRP category only. It does not diagnose cardiovascular disease, estimate an individual's absolute event risk, or determine treatment. Consider acute inflammatory conditions, assay context, the patient's full clinical profile, and current applicable guidelines.