hs-CRP Tertile Risk Category Calculator
Enter laboratory value
Classify the measured hs-CRP concentration using commonly used relative cardiovascular-risk categories.
mg/L
About hs-CRP risk categories
High-sensitivity C-reactive protein is a marker of systemic inflammation that can provide additional information for cardiovascular risk assessment. Commonly used categories describe lower, average, and higher relative risk; they do not replace a validated global risk assessment.
| hs-CRP concentration | Relative-risk category |
|---|---|
| <1.0 mg/L | Lower |
| 1.0–3.0 mg/L | Average |
| >3.0 mg/L | Higher |
Important interpretation points
- These cutoffs are commonly used relative-risk categories, not study-specific tertiles for every population.
- hs-CRP is nonspecific and may rise with infection, inflammatory disease, trauma, or other acute conditions.
- If the result is unexpectedly elevated during an acute illness, consider repeating measurement when clinically stable, according to clinical judgement and applicable guidance.
- Use this result as one component of risk assessment, not as a substitute for clinical judgement.
References
Ridker PM, Hennekens CH, Buring JE, Rifai N.
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836–843. doi:10.1056/NEJM200003233421202
Ridker PM.
A Test in Context: High-Sensitivity C-Reactive Protein. J Am Coll Cardiol. 2016;67(6):712–723. doi:10.1016/j.jacc.2015.11.037
Clinical disclaimer: This calculator provides a descriptive hs-CRP category only. It does not diagnose cardiovascular disease, estimate an individual's absolute event risk, or determine treatment. Consider acute inflammatory conditions, assay context, the patient's full clinical profile, and current applicable guidelines.
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