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hs-Troponin Delta Algorithm (0 to1-h and 0 to 2-h ESC models) Calculator

  • hs-Troponin at Presentation (ng/L)
  • hs-Troponin at 1 Hour (ng/L)
  • hs-Troponin at 2 Hours (ng/L)
  • hs-Troponin Delta Algorithm (0/1-h and 0/2-h ESC models): Explanation and Clinical Context
    The high-sensitivity troponin (hs-Tn) delta algorithms are validated tools to rapidly triage patients presenting with suspected non-ST-elevation acute coronary syndrome (NSTE-ACS).
    The 0/1-hour algorithm uses the baseline hs-Tn level and the absolute change after 1 hour to stratify patients into 'Rule-Out', 'Rule-In', or 'Observe'.
    Similarly, the 0/2-hour algorithm uses the baseline hs-Tn and the change at 2 hours. These algorithms enable early discharge of low-risk patients and timely intervention for high-risk patients.
    The cutoffs are based on ESC 2020 guidelines and derived from large prospective validation studies.

    Reference:
    Collet JP, Thiele H, Barbato E, et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J. 2021;42:1289-1367. doi:10.1093/eurheartj/ehaa575

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