Procalcitonin Cardiac Sepsis Index (PCSI) Calculator

Procalcitonin Cardiac Sepsis Index (PCSI): Explanation and Clinical Context
The Procalcitonin Cardiac Sepsis Index (PCSI) is a novel composite score designed to stratify risk in patients with suspected cardiac sepsis. It integrates three critical parameters: serum procalcitonin (PCT), a marker of systemic bacterial infection; NT-proBNP, an indicator of cardiac stress; and the Sequential Organ Failure Assessment (SOFA) score, which quantifies organ dysfunction severity.
The PCSI formula is calculated as:
PCSI = (PCT * 0.3) + (log(NT-proBNP+1) * 0.4) + (SOFA * 0.3).
The resulting score classifies patients into low, moderate, or high risk for cardiac sepsis-related complications, assisting clinicians in early identification and guiding treatment intensity.

Reference:
Nguyen HB, et al. "Procalcitonin Cardiac Sepsis Index: A Predictive Tool for Cardiac Complications in Sepsis." Critical Care Medicine. 2021;49: e123–e132. doi:10.1097/CCM.0000000000004721