REVEAL 2.0 Subscore Components Calculator

WHO Group 1 Subgroup

Male age > 60 years

eGFR < 60 mL/min/1.73m² or renal insufficiency

NYHA/WHO Functional Class

Systolic Blood Pressure (mm Hg) SBP =110 ? 0; SBP <110 ? 1

Heart Rate (beats/min) HR =96 ? 0; HR >96 ? 1

All-cause hospitalization = 6 months

6-Minute Walk Distance (meters) =440 ? -2; 320–440 ? -1; 165–319 ? 0; <165 ? 1

BNP (pg/mL) <50 ? -2; 50–199 ? 0; 200–799 ? 1; =800 ? 2

NT-proBNP (pg/mL) <300 ? -2; 300–1099 ? 0; =1100 ? 2

Pericardial effusion on echocardiography

DLCO (% predicted) <40% ? 1; =40% ? 0

Mean Right Atrial Pressure > 20 mmHg (within 1 year)

PVR (Wood units) <5 ? -1; =5 ? 0

REVEAL 2.0: Explanation and Clinical Context
REVEAL 2.0 is a validated, weighted risk model for pulmonary arterial hypertension (PAH) that integrates demographics, hemodynamics, and biomarkers to estimate 1-year mortality. Each parameter contributes positive or negative points depending on risk direction. The final score stratifies patients into low (0–6), intermediate (7–8), and high (=9) risk. The calculator above uses official cutoffs from the original Chest 2019 publication for accurate subscore modular computation.

Reference:
Benza RL, Gomberg-Maitland M, Elliott CG, et al. Predicting Survival in Patients With Pulmonary Arterial Hypertension: The REVEAL Risk Score Calculator 2.0. Chest. 2019;156(2):323–337.
Benza RL, Kanwar M, et al. REVEAL Lite 2: A Simplified, Noninvasive Version of the REVEAL 2.0 Score. Chest. 2021;160(1):66–79.

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