Cardiopulmonary Function Assessment Scores (CPET)

VO2/VE Ratio Index Calculator

Clinical calculation support · Verify results before clinical use

Ratio calculator

Enter oxygen uptake and minute ventilation from the same CPET time point. The result is a mathematical ratio, not a validated risk score.

—mL/L

—VO₂ / V̇E

Calculated ratio

Enter both values

The result will appear when both inputs are valid positive numbers.

Clinical note: No universal normal range or standalone prognostic cutoff for this ratio is provided here. Do not interpret it using the legacy 0.19–0.25 mL/L range without confirming the exact variable definition and units in the source protocol.

About the ratio

This calculator divides absolute oxygen uptake (VO₂, mL/min) by minute ventilation (V̇E, L/min), producing a value in mL O₂ per liter of ventilation (mL/L).

Use measurements from the same CPET time point and confirm that the source system reports VO₂ as an absolute value. If VO₂ is entered in mL/kg/min, the output is weight-normalized and cannot be labeled simply as mL/L.

Interpretation limits

This tool performs arithmetic only and does not assign a normal/abnormal category.
CPET interpretation should integrate symptoms, protocol, effort, gas-exchange data, and the clinical context.
Do not confuse VO₂/V̇E with the more established V̇E/VCO₂ relationship used in ventilatory-efficiency assessment.

References

Guazzi M, Adams V, Conraads V, et al.Clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations. Circulation. 2012;126:2261–2274. DOI: 10.1161/CIR.0b013e31826fb946.

Guazzi M, Arena R, Halle M, et al.2016 focused update: clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations. Circulation. 2016;133:e694–e711. DOI: 10.1161/CIR.0000000000000406.

ARTP statement on cardiopulmonary exercise testing 2021.CPET reporting and measurement variables. BMJ Open Respiratory Research. Full text.

Clinical disclaimer: This calculator is an aid for calculation only and is not a substitute for professional interpretation of cardiopulmonary exercise testing. Verify source units and measurement timing before using the result clinically.