Congestive Hepatopathy (Congestive Hepatic Fibrosis Score, CHFS) Calculator
- Congestive Hepatic Fibrosis Score (CHFS): explanation and clinical context
The CHFS is a histology-based grading system that stages fibrosis patterns seen in congestive hepatopathy on liver biopsy — it ranges from 0 (no fibrosis) through 4 (cirrhosis), with intermediate grades that distinguish centrizonal-limited fibrosis (stage 1), combined centrizonal and portal patterns with differing zone predominance (2A and 2B), and bridging fibrosis (3); CHFS correlates with measures of right-sided cardiac pressure/volume overload and provides a standardized, pathology-centered way to communicate severity of congestion-related liver remodeling, but it must always be interpreted in the clinical context because sampling heterogeneity is common and noninvasive tests (elastography, blood-based fibrosis markers) and hemodynamics add important complementary information.
Reference: Dai DF, Swanson P, Krieger EV, et al. Congestive hepatic fibrosis score: a novel histologic assessment of clinical severity. Mod Pathol. 2014;27:1552–1558. Additional reviews and validations discuss CHFS structure and clinical correlations.
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