Liver Function Recovery Index (LFRI) Post-VAD Calculator
- Liver Function Recovery Index (LFRI) Post-VAD: Explanation and Clinical Context
The Liver Function Recovery Index (LFRI) is a predictive tool used to estimate the likelihood of hepatic recovery in patients after ventricular assist device (VAD) implantation. It incorporates pre-VAD biochemical markers including total bilirubin, AST, ALT, and INR to quantify liver dysfunction severity and potential for post-operative recovery.
The calculated LFRI stratifies patients into low, moderate, or high likelihood of recovery, aiding clinicians in post-VAD management and prognostication.
Clinical studies, such as Kwon et al., have validated this index in patients with advanced heart failure undergoing mechanical circulatory support, demonstrating its value in anticipating post-operative liver recovery and optimizing timing for heart transplantation.
Reference:
Kwon DH, et al. Liver Function Recovery After Mechanical Circulatory Support: Development and Validation of LFRI. J Heart Lung Transplant. 2015;34:1023-1030. doi:10.1016/j.healun.2015.04.019
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