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APACHE II ICU Mortality Calculator

  • Age
  • Temperature core Celsius
  • Mean arterial pressure mm Hg
  • Heart rate beats per minute
  • Respiratory rate per minute
  • Fraction inspired oxygen FiO2 as decimal for example 0.21 for room air
  • PaO2 mm Hg leave empty if you will provide alveolar arterial gradient
  • A a gradient mm Hg provide only if FiO2 is 0.5 or greater
  • Arterial pH
  • Serum sodium mmol per L
  • Serum potassium mmol per L
  • Serum creatinine mg per dL
  • Hematocrit percent
  • White blood cell count in thousands per mm3 for example 12 for twelve thousand
  • Glasgow coma scale actual value 3 to 15
  • Chronic health status none enter 0 elective postoperative with severe organ insufficiency or immunocompromise enter 2 nonoperative or emergency postoperative with severe organ insufficiency or immunocompromise enter 5
  • Diagnostic category weight for example 0 for non operative patient 0 for elective postoperative patient 0.603 for emergency postoperative patient if applicable enter 0.603 otherwise enter 0
  • APACHE II score explanation and clinical context
    APACHE II is a severity scoring system developed to estimate risk of hospital mortality for patients admitted to intensive care. The score is the sum of an acute physiology score derived from the worst value in the first 24 hours for twelve physiologic variables plus points for age plus points for chronic health status. A higher total score indicates greater physiologic derangement and higher risk of death. The original method converts APACHE II into a predicted death probability using a logistic regression equation. The original formula uses logit equals negative 3.517 plus 0.146 times the APACHE II score plus an optional diagnostic category weight for certain operative categories. Predicted probability of death equals e to the logit divided by 1 plus e to the logit. Clinical use requires accurate worst value selection in the first 24 hours and careful interpretation because individual patient prognosis can vary and calibration may differ by local population and case mix. Use this tool as an adjunct to clinical judgement and local validation.

    Reference
    Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II a severity of disease classification system. Critical Care Medicine 1985;13:818 to 829.
    MSD Manual Professional edition APACHE II table.
    SFAR summary of logistic equation and predicted death rate.

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