About SYNTAX II Score:
The SYNTAX II Score combines anatomical and clinical variables to estimate 4-year mortality and guide revascularization strategy between PCI and CABG in patients with complex coronary artery disease. It improves upon the original SYNTAX I Score by incorporating key clinical parameters including age, sex, LVEF, renal function, COPD, PAD, and clinical presentation. Clinical Interpretation: A lower predicted mortality for PCI versus CABG indicates that percutaneous coronary intervention may be reasonable. Conversely, higher predicted mortality for PCI suggests that coronary artery bypass grafting may offer a better long-term outcome.
This score emphasizes a personalized, heart-team, based approach rather than anatomy alone. References:
1. Farooq V, et al. The SYNTAX II Score: A Novel Tool for Guiding the Revascularization Strategy in Patients with Complex Coronary Artery Disease. Eur Heart J. 2013;34(22):2824-2834.
2. Serruys PW, et al. SYNTAX II: A Prospective Validation of the SYNTAX II Score in the SYNTAX II Study. J Am Coll Cardiol. 2015;66(13):1509-1520.
3. SYNTAX Score Online Calculator. Available at: https://syntaxscore.org