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Simpson’s Biplane EF Calculator

1 Biplane LV Volume

Enter the LV end-diastolic and end-systolic volumes already obtained from the echocardiography report using the biplane method of disks (modified Simpson’s rule).

Important: This calculator does not reconstruct the Simpson biplane volume from separate 4-chamber and 2-chamber scalar volumes. The EDV and ESV entered here should be the final biplane values reported by the echocardiography system or laboratory.
Biplane EDV from echocardiography report, in mL.
Biplane ESV from echocardiography report, in mL.
2 Optional Parameters

These inputs are only required if you also want cardiac output, cardiac index, or indexed LV volumes.

Required for cardiac output (CO), in bpm.
Required for cardiac index and indexed LV volumes, in m².
i About Simpson’s Biplane LVEF
The biplane method of disks, also known as the modified Simpson’s rule, is the recommended two-dimensional echocardiographic method for LV volume assessment according to the ASE/EACVI chamber quantification recommendations. The method uses endocardial tracings from the apical four-chamber and apical two-chamber views and sums a series of disks to derive LV end-diastolic and end-systolic volumes.

This calculator therefore requires the final biplane EDV and ESV reported by the echocardiography system or laboratory. It does not calculate a Simpson biplane volume by simply averaging separate 4-chamber and 2-chamber volume numbers.
Clinical interpretation: The EF ranges shown by this calculator are descriptive LVEF ranges. They should not be interpreted as an independent diagnosis of HFrEF, HFmrEF, or HFpEF. In particular, the diagnosis of HF with preserved or mildly reduced EF requires appropriate clinical context and additional objective evidence when applicable.

R References
  1. Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28(1):1–39.e14.
  2. Heidenreich PA, Bozkurt B, Aguilar D, et al. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145:e895–e1032. doi:10.1161/CIR.0000000000001063.

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Appcardio may contain errors. Always verify the calculation and its accuracy before clinical use.