Pro-BNP Risk Score: Explanation and Clinical Context The Pro-BNP Risk Score is a validated clinical tool used to estimate the risk of adverse outcomes, including hospitalization and mortality, in patients with heart failure.
It is primarily based on serum NT-proBNP levels, reflecting myocardial wall stress, combined with clinical variables such as age. Higher NT-proBNP levels and older age are associated with increased risk.
This score allows clinicians to stratify patients into low, intermediate, or high-risk categories, guiding treatment intensity, follow-up frequency, and potential advanced therapy consideration.
Reference:
McDonagh TA, et al. NT-proBNP in the management of heart failure: clinical application and prognosis. Eur Heart J. 2018;39:350-358. doi:10.1093/eurheartj/ehx520
Maisel AS, et al. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med. 2002;347:161-167.