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Swedish PAH Registry Risk Model Calculator

  • WHO Functional Class (FC)
  • 6-Minute Walk Distance (6MWD, meters)
  • NT-proBNP (ng/L)
  • Right Atrial Pressure (RAP, mmHg)
  • Cardiac Index (CI, L/min/m²)
  • Mixed Venous O₂ Saturation (SvO₂, %)
  • Swedish PAH Registry Risk Model: Explanation and Clinical Context
    The Swedish PAH Registry Risk Model is a validated prognostic tool for patients with pulmonary arterial hypertension (PAH), developed from the Swedish Pulmonary Arterial Hypertension Registry (SPAHR). It integrates six key clinical and hemodynamic variables: WHO Functional Class (FC), 6-Minute Walk Distance (6MWD), NT-proBNP, Right Atrial Pressure (RAP), Cardiac Index (CI), and mixed venous oxygen saturation (SvO₂).
    Each parameter is scored based on thresholds that correlate with 1-year mortality risk. The mean of the six scores determines the overall risk category: low, intermediate, or high. This model helps clinicians stratify patients, guide treatment intensity, and monitor response to therapy.

    Reference:
    Kylhammar D, et al. “Risk assessment in pulmonary arterial hypertension: Data from the Swedish Pulmonary Arterial Hypertension Registry (SPAHR).” Eur Heart J. 2018;39:3299–3306. doi:10.1093/eurheartj/ehy234

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