VO2/VE Ratio Index Calculator
- VO₂/VE Ratio Index: Explanation and Clinical Context
The VO₂/VE Ratio Index represents the efficiency of oxygen uptake relative to ventilation during exercise. It is derived from cardiopulmonary exercise testing (CPET) by dividing oxygen consumption (VO₂ in mL/min/kg) by minute ventilation (VE in L/min).
A higher VO₂/VE ratio indicates more efficient gas exchange, while a lower ratio suggests ventilatory inefficiency, which can be seen in patients with heart failure, pulmonary hypertension, or respiratory disease.
Clinical interpretation involves assessing exercise tolerance, predicting prognosis, and guiding therapy in cardiopulmonary conditions. Normal values for healthy adults are approximately 0.19–0.25 mL/L, but this can vary with age, sex, and fitness level.
Reference:
Wasserman K, Hansen JE, Sue DY, et al. Principles of Exercise Testing and Interpretation, 5th Edition. Lippincott Williams & Wilkins, 2012; pp. 125-135.
Guazzi M, Adams V, Conraads V, et al. Clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations. Eur Heart J. 2012;33:2917–2927. doi:10.1093/eurheartj/ehs184
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