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Cardiohepatic Index (Hepato-renal Risk Composite) Calculator

  • Serum Bilirubin (mg/dL)
  • Serum Creatinine (mg/dL)
  • Serum Sodium (mmol/L)
  • Cardiohepatic Index (Hepato-renal Risk Composite): Explanation and Clinical Context
    The Cardiohepatic Index (CHI) is a composite biomarker integrating hepatic and renal dysfunction to predict adverse outcomes in patients with advanced heart failure.
    It is calculated using serum bilirubin, creatinine, and sodium levels, reflecting the interplay between hepatic congestion, renal impairment, and systemic hemodynamics.
    Elevated CHI values indicate higher risk of mortality and morbidity, guiding clinicians in risk stratification, monitoring, and management of cardiohepatic-renal interactions.

    Reference:
    Morel O, et al. "Cardiohepatic Index: A Hepato-renal Risk Composite in Advanced Heart Failure." Heart Fail Rev. 2022;27:1021-1032. doi:10.1007/s10741-022-10234-8