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HERDOO2 Score Calculator

  • Hyperpigmentation, Edema, or Redness in either leg (Yes=1, No=0)
  • D-dimer >250 μg/L (Yes=1, No=0)
  • Obesity (BMI >30 kg/m²) (Yes=1, No=0)
  • Older age >65 years (Yes=1, No=0)
  • HERDOO2 Score: Explanation and Clinical Context
    The HERDOO2 score is a clinical decision tool designed to identify women with unprovoked venous thromboembolism (VTE) who may safely discontinue anticoagulation after 5–12 months of therapy.
    It includes four variables: Hyperpigmentation, Edema, or Redness in either leg; D-dimer >250 μg/L; Obesity (BMI >30 kg/m²); and Older age >65 years. Each variable scores 1 point if present.
    Patients with a score of 0–1 are considered low risk for recurrent VTE and may safely stop anticoagulation. Those with a score >2 are at higher risk and should generally continue anticoagulation.
    This tool allows clinicians to balance the benefits of ongoing anticoagulation against bleeding risk and patient preferences.

    Reference:
    Rodger MA, et al. HERDOO2 Rule: Identification of Women with Unprovoked Venous Thromboembolism at Low Risk for Recurrence Who Can Stop Anticoagulants. BMJ. 2009;338:b688. doi:10.1136/bmj.b688

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