CS2 Score (Cardiogenic Shock Survival) Calculator

Age (years)

Confusion / altered mental status on presentation?

Previous myocardial infarction (MI) or CABG?

Acute coronary syndrome (ACS) as cause of shock?

Left ventricular ejection fraction (LVEF %)

Blood lactate (mmol/L)

Estimated GFR (mL/min/1.73 m²) — eGFR (CKD-EPI)

Prior stroke?

Admission glucose (mg/dL)

Serum creatinine (mg/dL)

TIMI flow < 3 after PCI? (if PCI performed)

Explanation and clinical context
The CardShock score was developed from a multicenter cohort to predict short-term mortality in patients with cardiogenic shock of various etiologies and uses seven admission variables (age, confusion, previous MI/CABG, ACS as cause, LVEF, lactate and eGFR). The IABP-SHOCK II score was derived from the IABP-SHOCK II trial in AMI-related cardiogenic shock; it uses variables available at admission (age, prior stroke, admission glucose, creatinine, lactate and TIMI flow after PCI). Both scores have been externally validated in multiple cohorts; each has specific scope and limitations (IABP-SHOCK II is AMI-specific and includes a post-PCI angiographic item). Use these scores to augment— not replace—clinical decision making. See references below for the original derivation and major validations.

References
Harjola V-P et al., CardShock study — Clinical picture and risk prediction of short-term mortality in cardiogenic shock (CardShock score). Eur Heart J / Eur J Heart Fail (CardShock publication).
Thiele H. et al., IABP-SHOCK II trial and derived risk score — IABP-SHOCK II risk score for 30-day mortality in AMI-related cardiogenic shock. (Trial publications and derived score descriptions).
External validations and comparative studies of CardShock and IABP-SHOCK II — multiple validation studies and reviews.

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