Duke Criteria (Modified Duke) Calculator

Major Criteria - Positive Blood Cultures

Major Criteria - Evidence of Endocardial Involvement

Minor Criteria - Predisposition (heart condition or IV drug use)

Minor Criteria - Fever >38°C

Minor Criteria - Vascular Phenomena (e.g., emboli, Janeway lesions)

Minor Criteria - Immunologic Phenomena (e.g., Osler nodes, Roth spots)

Minor Criteria - Microbiological Evidence Not Meeting Major Criteria

Duke Criteria (Modified Duke) Calculator: Explanation and Clinical Context
The Modified Duke Criteria is a widely accepted clinical tool for diagnosing infective endocarditis (IE) based on a combination of major and minor criteria.
Major criteria include positive blood cultures and evidence of endocardial involvement via echocardiography.
Minor criteria include predisposing heart conditions or IV drug use, fever >38°C, vascular phenomena (e.g., arterial emboli, Janeway lesions), immunologic phenomena (e.g., Osler nodes, Roth spots), and microbiologic evidence not meeting major criteria.
Definite IE is diagnosed if there are either 2 major criteria, 1 major plus 3 minor criteria, or 5 minor criteria.
Possible IE is considered with 1 major plus 1–2 minor criteria, or 3–4 minor criteria.
This calculator helps clinicians quickly stratify patients for further diagnostic work-up and management planning.

Reference:
Li JS, et al. Proposed Modifications to the Duke Criteria for the Diagnosis of Infective Endocarditis. Clin Infect Dis. 2000;30:633–638. doi:10.1086/313753

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