Dual-Energy CT Perfusion Defect Score (PH Correlate) Calculator
- Calculator mode
This tool supports two peer-reviewed approaches:
1) CTEPH segmental scoring (Abozeed et al., 2022): Perfusion Defect (PD) Score = number of segmental perfusion defects (0–18). Optional “Combined Score” adds clot-burden points (anatomic thrombus load) for stronger correlation with hemodynamics.
2) Perfusion Defect Percentage (Kim et al., 2014): Mean extent of perfusion defect across three coronal planes, estimated in 5% steps; correlates with TR Vmax and pulmonary artery size in pulmonary hypertension of mixed etiologies.
- Dual-Energy CT Perfusion Scoring: Explanation and Clinical Context
Dual-energy CT (DECT) generates iodine-based perfused-blood-volume (PBV) maps alongside standard CTPA anatomy, enabling semi-quantitative assessment of lung perfusion in pulmonary hypertension (PH). Two validated visual approaches are commonly used at the workstation. The first, designed for chronic thromboembolic PH (CTEPH), defines a Perfusion Defect (PD) Score by counting segmental perfusion defects (0–18) and optionally adds a weighted clot-burden score to form a Combined Score. The second approach expresses global disease burden as Perfusion Defect Percentage (PD%), averaging the visually estimated defect extent from three coronal planes in 5% increments.
Reference:
Abozeed M, Renapurkar RD, Heresi GA, et al. Cardiovasc Diagn Ther. 2022;12:462–474.
Kim EY, Seo JB, et al. Korean J Radiol. 2014;15:286–295.
Si-Mohamed SA, et al. Diagnostics. 2023;13:812.
Hoey ETD, et al. AJR. 2011;196:W384–W392.
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