Hypertriglyceridemic Waist (HTGW) Index Calculator

Clinical calculation support · Verify results before clinical use

Clinical assessment

Enter sex, waist circumference, and fasting triglycerides to assess the hypertriglyceridemic-waist phenotype.

Waist + TGHTGW criteria
The waist and triglyceride thresholds differ by sex.
Measure using a consistent, clinically appropriate protocol.
Use fasting triglycerides where possible; this phenotype uses lipid and waist measurements together.

About the HTGW phenotype

The hypertriglyceridemic-waist (HTGW) phenotype combines an enlarged waist circumference with elevated fasting triglycerides. It is used as a practical marker that may help identify people with an adverse cardiometabolic profile; it is not, by itself, a diagnosis of cardiovascular disease or a stand-alone risk calculator.

Thresholds used by this tool

CriterionMenWomen
Waist circumference≥90 cm≥85 cm
Triglycerides≥177 mg/dL (2.0 mmol/L)≥133 mg/dL (1.5 mmol/L)

HTGW-positive classification requires both the waist and triglyceride thresholds for the selected sex to be met. Thresholds can vary by population and study protocol; interpret them in the context of the applicable guideline and the patient's overall risk profile.

Clinical use

  • Consider the result alongside blood pressure, glycemia, lipid profile, smoking status, family history, and other established risk factors.
  • Confirm whether triglycerides were measured fasting and review secondary causes of hypertriglyceridemia when clinically indicated.
  • Use the finding to support, not replace, comprehensive cardiometabolic assessment and shared clinical decision-making.

References

Lemieux I, et al.Hypertriglyceridemic waist: a marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL). Circulation. 2007;116:667–675. doi:10.1161/CIRCULATIONAHA.106.675266
Clinical interpretation noteThe thresholds displayed here reflect the thresholds cited in the original tool's explanatory text. Their applicability may differ across populations; no universal diagnostic interpretation should be inferred.
Clinical disclaimer: This tool is for clinical education and decision support. HTGW classification is a phenotype marker, not a diagnosis and not a substitute for validated cardiovascular risk assessment. Verify measurement technique, fasting status, population-specific thresholds, and the full clinical context before making management decisions.